Laboratory of Optical Bioimaging and Spectroscopy
Deep Tissue Imaging Platform
Deep Tissue Imaging Platform
We are developing and applying novel deep tissue imaging platforms including:
We are developing and applying novel deep tissue imaging platforms including:
Isotope probed multiplex stimulated Raman scattering (ipm-SRS),
Isotope probed multiplex stimulated Raman scattering (ipm-SRS),
Multiphoton fluorescence (MPF),
Multiphoton fluorescence (MPF),
Enhanced stimulated Raman scattering (ESRS) microscopy.
Enhanced stimulated Raman scattering (ESRS) microscopy.
Drug Delivery
Drug Delivery
We use bioorthogonally-labeled SRS combined with multiphoton fluorescence microscopy to image drug delivery in animals.
We use bioorthogonally-labeled SRS combined with multiphoton fluorescence microscopy to image drug delivery in animals.
Two photon fluorescence imaging of brain microvessel ( Red is solutes injection into vessels) and astroctyes (Gcamp 6 ) in vivo in rodent,
Metabolism
Metabolism
We use label free and bioorthogonally-labeled SRS combined with multiphoton fluorescence microscopy to detect early stage in situ metabolic changes in aging, obesity, development, neurodegenerative diseases, cancer, and more.
We use label free and bioorthogonally-labeled SRS combined with multiphoton fluorescence microscopy to detect early stage in situ metabolic changes in aging, obesity, development, neurodegenerative diseases, cancer, and more.
